MabPurix Protein A

MabPurix A Series: Agarose-based Protein A Affinity Chromatography Resins
MabPurix P45 and MabPurix A65 affinity resins are based on spherical, highly cross-linked agarose beads with a narrow size distribution and high mechanical stability. The agarose base beads are covalently bonded with a base resistant recombinant Protein A through a proprietary method. MabPurix A affinity resins are specifically designed for purification applications of monoclonal antibodies and recombinant protein biomolecules containing Fc domains. Compared to other conventional agarose affinity resins, MabPurix A resins offer a better pressure resistance.

MabPurix P Series: Polymer-based Protein A Affinity Chromatography Resins
MabPurix P45 affinity resins are made from monodispersed porous polymethacrylate based beads with average particle sizes of 45 µm. The base beads are first treated with proprietary coating technology to provide hydrophilicity and bioinertness to avoid non-specific binding, and then are covalently bonded with a base resistant recombinant Protein A through a proprietary method. MabPurix P affinity resins are specifically designed for purification applications of monoclonal antibodies and recombinant protein biomolecules containing Fc domains.

Specification

• High DBC Capacity
• Low level of Protein A Leaching and residual HCP
• Hydrophilic, biocompatible, negligible non-specific binding
• High pH resistance (0.5 M NaOH)
• Low pressure
• High pressure resistance
• Supply capacity: >200 L/ batch

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