Proteomix® RP packings are porous polystyrene divinylbenzene (PS/DVB) polymer resins with narrow-dispersed particle size distribution. The base matrix of the resin is made of highly cross-linked PS/DVB which functions as reversed phase for chromatographic separation. The phase structure is phenyl and substituted phenyl functional groups that enable hydrophobic interaction. These highly rigid resins are provided with the particle size selection of 5, and 10 µm. In comparison to silica based reversed phase media, Proteomix® RP phases have advantages for biomolecule separations with wide pH range (1-14) and high thermal stability. At various column temperatures, the Proteomix® RP phases offer special selectivity, high resolution separation with online mass spec analysis capability for proteins such as mAb (monoclonal antibody), ADC (antibody drug conjugate) and related protein fragments.
Technical Specifications
Resin Matrix
Spherical, highly cross-linked PS/DVB
Pore size
300 Å, 500 Å and 1000 Å
Particle size
5 and 10 µm
Phase Structure
Phenyl and substituted phenyl group
Separation Mechanism
Hydrophobic interaction
pH Stability
1-14
Operating Temperature
Up to 80 °C
Operating Pressure
Up to 100 bar (at 80 °C )
Mobile Phase Compatibility
Compatible with aqueous solution, a mixture of water and acetonitrile, acetone, methanol, or THF
[1] Guard Cartridge with holder. [2] Guard column [3] One-piece PEEK coupler, recommended to connect columns in series. [4] PEEK/Stainless Steel coupler, recommended to connect columns of IDs > 7.8 mm in series. [5] Column coupler with 10cm length flexible tubing,10-32 fitting with 1/16 OD PEEK tubing. Recommended to connect analytical columns in series
[1] Guard Cartridge with holder. [2] Guard column [3] One-piece PEEK coupler, recommended to connect columns in series. [4] PEEK/Stainless Steel coupler, recommended to connect columns of IDs > 7.8 mm in series. [5] Column coupler with 10cm length flexible tubing,10-32 fitting with 1/16 OD PEEK tubing. Recommended to connect analytical columns in series
[1] Guard Cartridge with holder. [2] Guard column [3] One-piece PEEK coupler, recommended to connect columns in series. [4] PEEK/Stainless Steel coupler, recommended to connect columns of IDs > 7.8 mm in series. [5] Column coupler with 10cm length flexible tubing,10-32 fitting with 1/16 OD PEEK tubing. Recommended to connect analytical columns in series
