HP-SCX is a silica based mixed-mode strong cation exchange phase. The phase has a mixed chemical structure of sulfonic acid and phenyl group. The mixed mode of strong cation-exchange and hydrophobicity offers unique selectivity and high resolution separation for cationic/basic and nitrogen containing compounds as well as desirable retention for a variety of weak cationic and neutral organic compounds. The uniform polymeric bonding of HP-SCX enhances its stability under various separation conditions.
HP-SCX has expanded its applications from the traditional SCX separation of cationic and nitrogen containing compounds to weak cationic and neutral organic molecules. Examples include separation of analytes of amines and polyamines, such as alkaloids, peptides, codeine, and cough and cold ingredients.
Silica:
Sperical, high purity (<10 ppm metals)
Pore size:
120 Å
Particle size:
3 and 5 µm
Pore volume:
1.0 ml/g
Surface area:
300 m²/g
Phase structure:
Polymeric and mixed mode
% Carbon:
11.0%
Highly controlled chemistry of polymeric monolayer formation and end-capping
Mixed chemical structure of sulfonic acid and phenyl group
Mixed-mode of ion-exchange and hydrophobic interaction enables high selectivity and appropriate retention for a variety of compounds
High stability and reliable lot-to-lot consistency
pH stability: 1.5-8.0
Suitable for separations of a complex of cationic, nitrogen containing, and neutral compounds
[1] Guard column [2] One-piece PEEK coupler, recommended to connect columns in series. [3] PEEK/Stainless Steel coupler, recommended to connect columns of IDs > 7.8 mm in series. [4] Column coupler with 10cm length flexible tubing,10-32 fitting with 1/16 OD PEEK tubing. Recommended to connect analytical columns in series [5] For 21.2x10mm guard cartridge
[1] Guard column [2] Guard Cartridge only. [3] Guard Cartridge with holder. [4] One-piece PEEK coupler, recommended to connect columns in series. [5] PEEK/Stainless Steel coupler, recommended to connect columns of IDs > 7.8 mm in series. [6] Column coupler with 10cm length flexible tubing,10-32 fitting with 1/16 OD PEEK tubing. Recommended to connect analytical columns in series [7] For 21.2x10mm guard cartridge
[1] Guard column [2] Guard Cartridge only. [3] Guard Cartridge with holder. [4] One-piece PEEK coupler, recommended to connect columns in series. [5] PEEK/Stainless Steel coupler, recommended to connect columns of IDs > 7.8 mm in series. [6] Column coupler with 10cm length flexible tubing,10-32 fitting with 1/16 OD PEEK tubing. Recommended to connect analytical columns in series [7] For 21.2x10mm guard cartridge
[1] Guard column [2] One-piece PEEK coupler, recommended to connect columns in series. [3] PEEK/Stainless Steel coupler, recommended to connect columns of IDs > 7.8 mm in series. [4] Column coupler with 10cm length flexible tubing,10-32 fitting with 1/16 OD PEEK tubing. Recommended to connect analytical columns in series [5] For 21.2x10mm guard cartridge
