HP-SCX is a silica based mixed-mode strong cation exchange phase. The phase has a mixed chemical structure of sulfonic acid and phenyl group. The mixed mode of strong cation-exchange and hydrophobicity offers unique selectivity and high resolution separation for cationic/basic and nitrogen containing compounds as well as desirable retention for a variety of weak cationic and neutral organic compounds. The uniform polymeric bonding of HP-SCX enhances its stability under various separation conditions.

HP-SCX has expanded its applications from the traditional SCX separation of cationic and nitrogen containing compounds to weak cationic and neutral organic molecules. Examples include separation of analytes of amines and polyamines, such as alkaloids, peptides, codeine, and cough and cold ingredients.

Silica:	Sperical, high purity (<10 ppm metals)
Pore size:	120 Å
Particle size:	3 and 5 µm
Pore volume:	1.0 ml/g
Surface area:	300 m²/g
Phase structure:	Polymeric and mixed mode
% Carbon:	11.0%

• Highly controlled chemistry of polymeric monolayer formation and end-capping
• Mixed chemical structure of sulfonic acid and phenyl group
• Mixed-mode of ion-exchange and hydrophobic interaction enables high selectivity and appropriate retention for a variety of compounds
• High stability and reliable lot-to-lot consistency
• pH stability: 1.5-8.0
• Suitable for separations of a complex of cationic, nitrogen containing, and neutral compounds

HP-SCX      1.8 µm         2.2 µm         3 µm         5 µm         10 µm

Sepax HP-SCX Sign In to see pricing Part Number Particle Size Pore Size ID×Length 120361-2103 1.8 µm 120 Å 2.1×30mm 120361-2105 1.8 µm 120 Å 2.1×50mm 120361-2110 1.8 µm 120 Å 2.1×100mm 120361-2115 1.8 µm 120 Å 2.1×150mm 120361-3003 1.8 µm 120 Å 3.0×30mm 120361-3005 1.8 µm 120 Å 3.0×50mm 120361-3010 1.8 µm 120 Å 3.0×100mm 120361-3015 1.8 µm 120 Å 3.0×150mm 120361-4603 1.8 µm 120 Å 4.6×30mm 120361-4605 1.8 µm 120 Å 4.6×50mm 120361-4610 1.8 µm 120 Å 4.6×100mm 120361-4615 1.8 µm 120 Å 4.6×150mm Sepax HP-SCX Sign In to see pricing Part Number Particle Size Pore Size ID×Length 120362-2103 2.2 µm 120 Å 2.1×30mm 120362-2105 2.2 µm 120 Å 2.1×50mm 120362-2110 2.2 µm 120 Å 2.1×100mm 120362-2115 2.2 µm 120 Å 2.1×150mm 120362-3003 2.2 µm 120 Å 3.0×30mm 120362-3005 2.2 µm 120 Å 3.0×50mm 120362-3010 2.2 µm 120 Å 3.0×100mm 120362-3015 2.2 µm 120 Å 3.0×150mm 120362-4603 2.2 µm 120 Å 4.6×30mm 120362-4605 2.2 µm 120 Å 4.6×50mm 120362-4610 2.2 µm 120 Å 4.6×100mm 120362-4615 2.2 µm 120 Å 4.6×150mm Sepax HP-SCX Sign In to see pricing Part Number Particle Size Pore Size ID×Length 120363-2001 [1] 3 µm 120 Å 2.0×10mm 120363-2001C [2] 3 µm 120 Å 2.0×10mm 120363-2103 3 µm 120 Å 2.1×30mm 120363-2105 3 µm 120 Å 2.1×50mm 120363-2110 3 µm 120 Å 2.1×100mm 120363-2115 3 µm 120 Å 2.1×150mm 120363-2125 3 µm 120 Å 2.1×250mm 120363-3003 3 µm 120 Å 3.0×30mm 120363-3005 3 µm 120 Å 3.0×50mm 120363-3010 3 µm 120 Å 3.0×100mm 120363-3015 3 µm 120 Å 3.0×150mm 120363-3025 3 µm 120 Å 3.0×250mm 120363-4001 [1] 3 µm 120 Å 4.0×10mm 120363-4001C [2] 3 µm 120 Å 4.0×10mm 120363-4603 3 µm 120 Å 4.6×30mm 120363-4605 3 µm 120 Å 4.6×50mm 120363-4610 3 µm 120 Å 4.6×100mm 120363-4615 3 µm 120 Å 4.6×150mm 120363-4625 3 µm 120 Å 4.6×250mm [1]: Guard Cartridge only. [2]: Guard Cartridge with holder (Part number ended with "C"). Precolumn Filters (Alternative choice for Guard Cartridge) P/N#: 102000-P355 (2 µm PEEK frit), $65.00/ea     - for column with particle size 5 µm and 10 µm. P/N#: 102000-P356 (0.5 µm PEEK frit), $65.00/ea     - for column with particle size 3 µm, or less than 3 µm. PEEK Refill Frits (For Precolumn Filter) P/N#: 102001-P355, 2 µm, 5 units/pk, $100/pk P/N#: 102001-P356, 0.5 µm, 5 units/pk, $100/pk Sepax HP-SCX Sign In to see pricing Part Number Particle Size Pore Size ID×Length 120365-2001 [1] 5 µm 120 Å 2.0×10mm 120365-2001C [2] 5 µm 120 Å 2.0×10mm 120365-2103 5 µm 120 Å 2.1×30mm 120365-2105 5 µm 120 Å 2.1×50mm 120365-2110 5 µm 120 Å 2.1×100mm 120365-2115 5 µm 120 Å 2.1×150mm 120365-2125 5 µm 120 Å 2.1×250mm 120365-3003 5 µm 120 Å 3.0×30mm 120365-3005 5 µm 120 Å 3.0×50mm 120365-3010 5 µm 120 Å 3.0×100mm 120365-3015 5 µm 120 Å 3.0×150mm 120365-3025 5 µm 120 Å 3.0×250mm 120365-4001 [1] 5 µm 120 Å 4.0×10mm 120365-4001C [2] 5 µm 120 Å 4.0×10mm 120365-4603 5 µm 120 Å 4.6×30mm 120365-4605 5 µm 120 Å 4.6×50mm 120365-4610 5 µm 120 Å 4.6×100mm 120365-4615 5 µm 120 Å 4.6×150mm 120365-4625 5 µm 120 Å 4.6×250mm 120365-7815 5 µm 120 Å 7.8×150mm 120365-7825 5 µm 120 Å 7.8×250mm 120365-10005 5 µm 120 Å 10.0×50mm 120365-10010 5 µm 120 Å 10.0×100mm 120365-10015 5 µm 120 Å 10.0×150mm 120365-10025 5 µm 120 Å 10.0×250mm 120365-21201 [1] 5 µm 120 Å 21.2×10mm 120365-21205 5 µm 120 Å 21.2×50mm 120365-21210 5 µm 120 Å 21.2×100mm 120365-21215 5 µm 120 Å 21.2×150mm 120365-21225 5 µm 120 Å 21.2×250mm 120365-30005 5 µm 120 Å 30.0×50mm 120365-30010 5 µm 120 Å 30.0×100mm 120365-30015 5 µm 120 Å 30.0×150mm 120365-30025 5 µm 120 Å 30.0×250mm [1] Need guard cartridge holder P/N#: 102000-21201 Price: $220.00/EA (for 21.2×10mm guard cartridge) Sepax HP-SCX Sign In to see pricing Part Number Particle Size Pore Size ID×Length 120369-7815 10 µm 120 Å 7.8×150mm 120369-7825 10 µm 120 Å 7.8×250mm 120369-10005 10 µm 120 Å 10.0×50mm 120369-10010 10 µm 120 Å 10.0×100mm 120369-10015 10 µm 120 Å 10.0×150mm 120369-10025 10 µm 120 Å 10.0×250mm 120369-21205 10 µm 120 Å 21.2×50mm 120369-21210 10 µm 120 Å 21.2×100mm 120369-21215 10 µm 120 Å 21.2×150mm 120369-21225 10 µm 120 Å 21.2×250mm 120369-30005 10 µm 120 Å 30.0×50mm 120369-30010 10 µm 120 Å 30.0×100mm 120369-30015 10 µm 120 Å 30.0×150mm 120369-30025 10 µm 120 Å 30.0×250mm

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