Sepax GP-C18 HPLC Columns

GP-C18 uses full coverage bonded silica packing, which provides exceptionally high stability. Figure 1 shows the highly reproducible retention time for three standard compounds: aniline, anisole and toluene after 13,000 column volume runs in a mobile phase of 85% methanol and 15% water. Such high stability allows GP-C18 extremely suitable for validation of various analytes.

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Silica:	Spherical, high purity (<10 ppm metals)
Pore size:	120Å
Particle size:	1.8, 2.2, 3, 4, 5, 7, and 10 µm
Pore volume:	1.0 ml/g
Surface area:	300 m²/g
Phase structure:	Monomeric and fully endcapped
% Carbon:	17%

The unique mono-functional bonding chemistry of GP-C18 avoids the formation of multiple C18 layers. Such uniform stationary phase allows the separation to achieve high selectivity and high efficiency. A typical test chromatogram for quality control is shown here using a 4.6×250mm GP-C18 column.

• Highly controlled chemistry of monolayer formation and end-capping
• Extremely high column-to-column reproducibility
• High selectivity and efficiency for separations
• Suitable for separations of acidic, neutral and basic organic compounds, as well as pharmaceuticals, peptides, and others
• Recommended for separations in organic or mixed organic/aqueous mobile phases.

SepaxGP-C18 uses full coverage bonded silica packing, which provides exceptionally high stability. Figure below shows the highly reproducible retention time for three standard compounds: aniline, anisole and toluene after 13,000 column volume runs in a mobile phase of 85% methanol and 15% water. Such high stability allows SepaxGP-C18 extremely suitable for validation of various analytes.

Selectivity is very important for detection of the components of low abundance and impurities from the analysis of pharmaceuticals in the real applications. The comparative tests shown below from the method development of a drug molecule clearly demonstrated that GP-C18 is among the best products for high selectivity and sensitivity in detecting low abundant components and the impurities.

Organic Acids
Purine Alkaloids
Catecholamines
Pharmaceuticals
Simvastatin
Elevated Temperature

Sepax GP-C18 Part Number Particle Size Pore Size ID×Length Price 101183-2001 * 3 µm 120Å 2.0×10mm $165.00 101183-2103 3 µm 120Å 2.1×30mm $350.00 101183-2105 3 µm 120Å 2.1×50mm $350.00 101183-2110 3 µm 120Å 2.1×100mm $415.00 101183-2115 3 µm 120Å 2.1×150mm $460.00 101183-2125 3 µm 120Å 2.1×250mm $515.00 101183-3003 3 µm 120Å 3.0×30mm $350.00 101183-3005 3 µm 120Å 3.0×50mm $350.00 101183-3010 3 µm 120Å 3.0×100mm $415.00 101183-3015 3 µm 120Å 3.0×150mm $460.00 101183-3025 3 µm 120Å 3.0×250mm $515.00 101183-4001 * 3 µm 120Å 4.0×10mm $165.00 101183-4603 3 µm 120Å 4.6×30mm $350.00 101183-4605 3 µm 120Å 4.6×50mm $350.00 101183-4610 3 µm 120Å 4.6×100mm $415.00 101183-4615 3 µm 120Å 4.6×150mm $460.00 101183-4625 3 µm 120Å 4.6×250mm $515.00 * Guard cartridge holder needed. Guard cartridge holder P/N#: 102000-2001, $42.50/EA, for 2.0×10mm guard cartridge P/N#: 102000-4001, $42.50/EA, for 4.0×10mm guard cartridge Sepax GP-C18 Part Number Particle Size Pore Size ID×Length Price 101184-2001 * 4 µm 120Å 2.0×10mm $165.00 101184-2103 4 µm 120Å 2.1×30mm $350.00 101184-2105 4 µm 120Å 2.1×50mm $350.00 101184-2110 4 µm 120Å 2.1×100mm $415.00 101184-2115 4 µm 120Å 2.1×150mm $460.00 101184-2125 4 µm 120Å 2.1×250mm $515.00 101184-3003 4 µm 120Å 3.0×30mm $350.00 101184-3005 4 µm 120Å 3.0×50mm $350.00 101184-3010 4 µm 120Å 3.0×100mm $415.00 101184-3015 4 µm 120Å 3.0×150mm $460.00 101184-3025 4 µm 120Å 3.0×250mm $515.00 101184-4001 * 4 µm 120Å 4.0×10mm $165.00 101184-4603 4 µm 120Å 4.6×30mm $350.00 101184-4605 4 µm 120Å 4.6×50mm $350.00 101184-4610 4 µm 120Å 4.6×100mm $415.00 101184-4615 4 µm 120Å 4.6×150mm $460.00 101184-4625 4 µm 120Å 4.6×250mm $515.00 * Guard cartridge holder needed. Guard cartridge holder P/N#: 102000-2001, $42.50/EA, for 2.0×10mm guard cartridge P/N#: 102000-4001, $42.50/EA, for 4.0×10mm guard cartridge Sepax GP-C18 Part Number Particle Size Pore Size ID×Length Price 101185-2001 * 5 µm 120Å 2.0×10mm $165.00 101185-2103 5 µm 120Å 2.1×30mm $330.00 101185-2105 5 µm 120Å 2.1×50mm $330.00 101185-2110 5 µm 120Å 2.1×100mm $390.00 101185-2115 5 µm 120Å 2.1×150mm $445.00 101185-2125 5 µm 120Å 2.1×250mm $500.00 101185-3003 5 µm 120Å 3.0×30mm $330.00 101185-3005 5 µm 120Å 3.0×50mm $330.00 101185-3010 5 µm 120Å 3.0×100mm $390.00 101185-3015 5 µm 120Å 3.0×150mm $445.00 101185-3025 5 µm 120Å 3.0×250mm $500.00 101185-4001 * 5 µm 120Å 4.0×10mm $165.00 101185-4603 5 µm 120Å 4.6×30mm $330.00 101185-4605 5 µm 120Å 4.6×50mm $330.00 101185-4610 5 µm 120Å 4.6×100mm $390.00 101185-4615 5 µm 120Å 4.6×150mm $445.00 101185-4625 5 µm 120Å 4.6×250mm $500.00 * Guard cartridge holder needed. Guard cartridge holder P/N#: 102000-2001, $42.50/EA, for 2.0×10mm guard cartridge P/N#: 102000-4001, $42.50/EA, for 4.0×10mm guard cartridge Sepax GP-C18 Part Number Particle Size Pore Size ID×Length Price 101185-7815 5 µm 120Å 7.8×150mm $910.00 101185-7825 5 µm 120Å 7.8×250mm $1,040.00 101185-10005 5 µm 120Å 10.0×50mm $525.00 101185-10010 5 µm 120Å 10.0×100mm $910.00 101185-10015 5 µm 120Å 10.0×150mm $1,030.00 101185-10025 5 µm 120Å 10.0×250mm $1,265.00 101185-21201 * 5 µm 120Å 21.2×10mm $305.00 101185-21205 5 µm 120Å 21.2×50mm $1,515.00 101185-21210 5 µm 120Å 21.2×100mm $2,040.00 101185-21215 5 µm 120Å 21.2×150mm $2,305.00 101185-21225 5 µm 120Å 21.2×250mm $2,695.00 101185-30005 5 µm 120Å 30.0×50mm $2,530.00 101185-30010 5 µm 120Å 30.0×100mm $3,085.00 101185-30015 5 µm 120Å 30.0×150mm $3,910.00 101185-30025 5 µm 120Å 30.0×250mm $5,330.00 * Guard cartridge holder needed. Guard cartridge holder P/N#: 102000-21201 Price: $175.00/EA (for 21.2×10mm guard cartridge) Sepax GP-C18 Part Number Particle Size Pore Size ID×Length Price 101187-7815 7 µm 120Å 7.8×150mm $765.00 101187-7825 7 µm 120Å 7.8×250mm $940.00 101187-10005 7 µm 120Å 10.0×50mm $435.00 101187-10010 7 µm 120Å 10.0×100mm $765.00 101187-10015 7 µm 120Å 10.0×150mm $985.00 101187-10025 7 µm 120Å 10.0×250mm $1,265.00 101187-21201 * 7 µm 120Å 21.2×10mm $305.00 101187-21205 7 µm 120Å 21.2×50mm $1,185.00 101187-21210 7 µm 120Å 21.2×100mm $1,735.00 101187-21215 7 µm 120Å 21.2×150mm $2,065.00 101187-21225 7 µm 120Å 21.2×250mm $2,305.00 101187-30025 7 µm 120Å 30.0×250mm Inquire * Guard cartridge holder needed. Guard cartridge holder P/N#: 102000-21201 Price: $175.00/EA (for 21.2×10mm guard cartridge) Sepax GP-C18 Part Number Particle Size Pore Size ID×Length Price 101189-7815 10 µm 120Å 7.8×150mm $635.00 101189-7825 10 µm 120Å 7.8×250mm $765.00 101189-10005 10 µm 120Å 10.0×50mm $415.00 101189-10010 10 µm 120Å 10.0×100mm $690.00 101189-10015 10 µm 120Å 10.0×150mm $875.00 101189-10025 10 µm 120Å 10.0×250mm $1,020.00 101189-21205 10 µm 120Å 21.2×50mm $1,045.00 101189-21210 10 µm 120Å 21.2×100mm $1,625.00 101189-21215 10 µm 120Å 21.2×150mm $1,820.00 101189-21225 10 µm 120Å 21.2×250mm $2,145.00 101189-30005 10 µm 120Å 30.0×50mm $2,040.00 101189-30010 10 µm 120Å 30.0×100mm $2,530.00 101189-30015 10 µm 120Å 30.0×150mm $3,495.00 101189-30025 10 µm 120Å 30.0×250mm $4,265.00

Analytical GP-C18, 3µm GP-C18, 4µm GP-C18, 5µm Prep/Semi-prep GP-C18, 5µm GP-C18, 7µm GP-C18, 10µm