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With butyl group chemically attached to of the modified non-porous poly(styrene divinylbenzene) (PS/DVB) beads, Proteomix® HIC Butyl columns provide high resolution hydrophobic interaction separation for biomolecules such as mAb, ADCs and their fragments.   Utilizing innovative chemistry and proprietary coating, 3 µm Zenix®-C SEC lines are ideal for the separation of hydrophobic samples, such as ADCs (Antibody Drug Conjugates), membrane proteins, and PEGlylated proteins. Zenix®-C lines have pore size selection of 300, 150, 100 and 80 Å. A full Antibody Drug Conjugates (ADCs) chromatographic separation solution includes Zenix®-C SEC for analysis of ADCs aggregate, monomer, fragment and free drug, Proteomix® HIC Butyl and RP-1000 for Drug to Antibody Ratio (DAR) analysis, and Proteomix® and Antibodix® IEX for ADCs charge variants studies.
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