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Samples

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Sample: ADC

ADC

Recommended products

Size Exclusion:    Zenix    Zenix-C    SRT    SRT-C    Preparative SEC
Ion Exchange:    Proteomix    Antibodix
Reversed phase:    Proteomix RP    Bio-C4
Hydrophobic Interaction:    Proteomix HIC

Application ID:

ZM1019

Title:

Analytical Characterization of Antibody Drug Conjugates

Separation Mode:

Size Exclusion, Ion Exchange, Reversed Phase

Brand:

Zenix-C Proteomix Proteomix RP

Topic:

Method Optimization, Volatile Buffer, Packing Chemistry, Fast Assay, MAb Fragment, Charge Variants, Aggregates, Resolution, Competition Comparison, Orthogonal Method

Column:

233300-7830	Zenix-C SEC-300, 3 µm, 300 Å, 7.8 x 300 mm
233080-4605	Zenix-C SEC-80, 3 µm, 80 Å, 4.6 x 50 mm
401NP5P-4625	Proteomix SCX NP5, 5 µm, 4.6 x 250 mm PEEK
465950-4610	Proteomix RP-1000, 5 µm, 4.6 x 100 mm

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Application ID:

EM1003

Title:

Herceptin Analysis on ZenixTM SEC-300 (7830)

Separation Mode:

Ion Exchange

Brand:

Zenix

Topic:

Herceptin Analysis

Column:

213300-7830	Zenix SEC-300, 3um, 300 A 7.8 x 300 mm
233300-7830	Zenix-C SEC-300, 3 um, 7.8, x, 300 mm

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Application ID:

WM1002

Title:

ADC Separation on Unix-C SEC-300

Separation Mode:

Size Exclusion

Brand:

Unix-C

Topic:

Resolution, Aggregates, Competition Comparison, Column Stability, Lot to Lot, Particle Size Impact, Loading

Column:

231300-4630

UHPLC Column, Sepax, Unix-C SEC-300 1.8 µm 300 Å 4.6x150 mm

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Application ID:

ZM1024

Title:

Intact MAb, ADC and their Fragment Analysis with SEC-MS

Separation Mode:

Size Exclusion, Size Exclusion, Size Exclusion, Size Exclusion

Brand:

Zenix Zenix-C

Topic:

MAb Fragment, Resolution, Volatile Buffer, Method Optimization

Column:

213300-7830	Zenix SEC-300, 3 µm, 300 Å, 7.8 x 300 mm
213300-4630	Zenix SEC-300, 3 µm, 300 Å, 4.6 x 300 mm
233300-4630	Zenix-C SEC-300, 3 µm, 300 Å, 4.6 x 300 mm
233300-2130	Zenix-C SEC-300, 3 µm, 300 Å, 2.1 x 300 mm

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Application ID:

ZM1023

Title:

ADC vs. Free Drug Analysis

Separation Mode:

Size Exclusion, Size Exclusion, Size Exclusion

Brand:

Zenix Zenix-C

Topic:

Resolution, Volatile Buffer, Pore Size Selection, Fast Assay, Method Optimization, Loading

Column:

213080-2105	Zenix SEC-80, 3 µm, 80 Å, 2.1 x 50 mm
233080-4605	Zenix-C SEC-80, 3 µm, 80 Å, 4.6 x 50 mm
213080-7805	Zenix SEC-80, 3 µm, 80 Å, 7.8 x 50 mm

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Application ID:

PM1016

Title:

Intact MAb, ADC and their Fragments Analysis on RP LC/MS

Separation Mode:

Hydrophobic Interaction, Reversed Phase, Reversed Phase

Brand:

Proteomix HIC Proteomix RP

Topic:

MAb Fragment, Resolution, Volatile Buffer, Method Optimization

Column:

431NP5-4603	Proteomix HIC Butyl-NP5, 5 µm, NP, 4.6 x 35 mm
465950-2105	Proteomix RP-1000, 5 µm, 1000 Å, 2.1 x 50 mm
465950-4610	Proteomix RP-1000, 5 µm, 1000 Å, 4.6 x 100 mm

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Application ID:

ZM1022

Title:

MAb/ADC Fragment Separation after IDeS Digestion

Separation Mode:

Size Exclusion, Size Exclusion, Hydrophobic Interaction, Reversed Phase

Brand:

Zenix Zenix-C Proteomix HIC Proteomix RP

Topic:

MAb Fragment, Resolution, Volatile Buffer

Column:

213300-7830	Zenix SEC-300, 3 µm, 300 Å, 7.8 x 300 mm
233300-4630	Zenix-C SEC-300, 3 µm, 300 Å, 4.6 x 300 mm
431NP5-4603	Proteomix HIC Butyl-NP5, 5 µm, NP, 4.6 x 35 mm
465950-2105	Proteomix RP-1000, 5 µm, 1000 Å, 2.1 x 50 mm

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Application ID:

HICM1001

Title:

ADC/MAb Separation on Proteomix HIC

Separation Mode:

Hydrophobic Interaction

Brand:

Proteomix Proteomix HIC

Topic:

Lot to Lot, Competition Comparison, Resolution

Column:

431NP5-4603	Proteomix HIC Butyl, NP5, 4.6 x 35 mm
433NP5-4603	Proteomix HIC Phenyl, NP5, 4.6x35mm
432NP5-4603	Proteomix HIC Ethyl, NP5, 4.6x35mm
434NP5-4603	Proteomix HIC Propyl, NP5, 4.6x35mm

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Application ID:

PM1013

Title:

Intact and Reduced MAb/ADC and MAb Fragment Separation on RP

Separation Mode:

Reversed Phase

Brand:

Proteomix Proteomix RP

Topic:

Method Optimization, Volatile Buffer, Packing Chemistry, Fast Assay, MAb Fragment, Orthogonal Method

Column:

465950-4605	Proteomix RP-1000, 5 µm, 1000 Å, 4.6 x 50 mm
465950-4610	Proteomix RP-1000, 5 µm, 1000 Å, 4.6 x 100 mm
465950-2105	Proteomix RP-1000, 5 µm, 1000 Å, 2.1 x 50 mm
110045-4610	Bio-C4, 5um, 300 A 4.6 x 100 mm

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Application ID:

EM1004

Title:

Herceptin-Lysine ADC Analysis by Zenix-C and TSKgel

Separation Mode:

Size Exclusion

Brand:

Zenix-C

Topic:

Competition Comparison, Resolution, Packing Chemistry, Aggregates, Method Optimization

Column:

233300-7830

Zenix-C SEC-300, 3 µm, 300 Å, 7.8 x 300 mm

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Application ID:

PM1011

Title:

Herceptin-Cysteine ADC Charge Variants Separation on SCX

Separation Mode:

Ion Exchange

Brand:

Proteomix

Topic:

Charge Variants

Column:

401NP5-4625

Proteomix SCX NP5, 5 µm, 4.6 x 250 mm

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Application ID:

ZM1018

Title:

MAb and its ADCs Separation on SEC

Separation Mode:

Size Exclusion

Brand:

Zenix Zenix-C

Topic:

Resolution, Packing Chemistry, Aggregates, Method Optimization

Column:

213300-7830	Zenix SEC-300, 3 µm, 300 Å, 7.8 x 300 mm
233300-7830	Zenix-C SEC-300, 3 µm, 300 Å, 7.8 x 300 mm

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Application ID:

EM1002

Title:

ADC Analysis on Zenix-C SEC

Separation Mode:

Size Exclusion

Brand:

Zenix Zenix-C

Topic:

Resolution, Packing Chemistry, Aggregates, Method Optimization

Column:

213300-7830	Zenix SEC-300, 3 µm, 300 Å, 7.8 x 300 mm
233300-7830	Zenix-C SEC-300, 3 µm, 300 Å, 7.8 x 300 mm

Back to Recommended products page

Application Note

Featured Application Notes

Analytical Characterization of Antibody Drug Conjugates

All Application Notes

Separation Mode

Brand

Topic

Equipment

App ID

Title

Size Exclusion@Ion Exchange@Reversed PhaseZenix-C@Proteomix@Proteomix RPMethod Optimization@Volatile Buffer@Packing Chemistry@Fast Assay@MAb Fragment@Charge Variants@Aggregates@Resolution@Competition Comparison@Orthogonal MethodHPLC@LCMS1Ion ExchangeZenixHerceptin AnalysisHPLC1Size ExclusionUnix-CResolution@Aggregates@Competition Comparison@Column Stability@Lot to Lot@Particle Size Impact@LoadingUHPLC1Size Exclusion@Size Exclusion@Size Exclusion@Size ExclusionZenix@Zenix-CMAb Fragment@Resolution@Volatile Buffer@Method Optimization HPLC@LCMS1Size Exclusion@Size Exclusion@Size ExclusionZenix@Zenix-CResolution@Volatile Buffer@Pore Size Selection@Fast Assay@Method Optimization@Loading HPLC@LCMS1Hydrophobic Interaction@Reversed Phase@Reversed PhaseProteomix HIC@Proteomix RPMAb Fragment@Resolution@Volatile Buffer@Method OptimizationHPLC@LCMS1Size Exclusion@Size Exclusion@Hydrophobic Interaction@Reversed PhaseZenix@Zenix-C@Proteomix HIC@Proteomix RPMAb Fragment@Resolution@Volatile BufferHPLC/LCMS1Hydrophobic InteractionProteomix@Proteomix HICLot to Lot@Competition Comparison@ResolutionHPLC1Reversed PhaseProteomix@Proteomix RPMethod Optimization@Volatile Buffer@Packing Chemistry@Fast Assay@MAb Fragment@Orthogonal MethodHPLC@LCMS@NanoLC1Size ExclusionZenix-CCompetition Comparison@Resolution@Packing Chemistry@Aggregates@Method OptimizationHPLC1Ion ExchangeProteomixCharge VariantsHPLC1Size ExclusionZenix@Zenix-CResolution@Packing Chemistry@Aggregates@Method OptimizationHPLC1Size ExclusionZenix@Zenix-CResolution@Packing Chemistry@Aggregates@Method OptimizationHPLC11311

ZM1019	Analytical Characterization of Antibody Drug Conjugates
EM1003	Herceptin Analysis on ZenixTM SEC-300 (7830)
WM1002	ADC Separation on Unix-C SEC-300
ZM1024	Intact MAb, ADC and their Fragment Analysis with SEC-MS
ZM1023	ADC vs. Free Drug Analysis
PM1016	Intact MAb, ADC and their Fragments Analysis on RP LC/MS
ZM1022	MAb/ADC Fragment Separation after IDeS Digestion
HICM1001	ADC/MAb Separation on Proteomix HIC
PM1013	Intact and Reduced MAb/ADC and MAb Fragment Separation on RP
EM1004	Herceptin-Lysine ADC Analysis by Zenix-C and TSKgel
PM1011	Herceptin-Cysteine ADC Charge Variants Separation on SCX
ZM1018	MAb and its ADCs Separation on SEC
EM1002	ADC Analysis on Zenix-C SEC

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